PHYTOCHEMICAL ANALYSIS AND ESTIMATION OF ANTI OXIDANT POTENTIAL OF PHYTOSOMES FORMULATIONS OF MORINDA LUCIDA BENTH

Introduction: Lucid morinda (L) A medium-sized evergreen tree of the Morinda genus, Benth (M. lucida, Rubiaceae) is a tropical West African rainforest plant that also known as Brimstone tree. In several nations, it utilized in traditional medicine to cure variety human ailments. Phytosomes are freshly developed herbal formulations have superior bioavailability and effects than phyto molecules or botanical extracts because they more readily absorbed. The goals current study were evaluate ethanolic leaf extract M. lucida's phytosomes, vitro antioxidant properties, qualitative quantitative phytochemical analyses, phytosome formation. Methods: cholesterol-containing phospholipids used make phytosome. entrapment efficiency, particle size distribution, optical microscopic research, stability tests, dissolution investigations characterize phytosomes. Alkaloids, glycosides, sterols, phenols, terpenoids, tannins, saponins found by examination. Results: lucida contained 0.721 mg total phenols 0.464 alkaloids per 100 mg. Using industry-standard procedures, extract's activity was evaluated against DPPH assay technique. Combining can synergistic impact, which be measured using model for free radical scavenging activity. optimised batch F10's efficiency 223.30±0.41 nm 76.46±0.61 nm, respectively. Conclusion: It employed targeted delivery system future applications such liver, brain, heart, etc. protection. use novel approaches rather methods delivering drugs increases polar boosts patient compliance. Peer Review History: Received: 28 October 2022; Revised: 27 November; Accepted: 3 January 2023, Available online: 15 2023 Academic Editor: Dr. Gehan Fawzy Abdel Raoof Kandeel, Pharmacognosy Department, National Research Centre, Dokki, 12622, Giza, Egypt, [email protected] Received file: Reviewer's Comments: Average review marks at initial stage: 5.5/10 publication 7.0/10 Reviewers: George Zhu, Tehran University Medical Sciences, Tehran, Iran, [email protected] Hasniza Zaman Huri, Malaya Kuala Lumpur, [email protected] Similar Articles: NUTRITIONAL COMPOSITION, CONSTITUENTS, AND ANTIOXIDANT ACTIVITY OF POWDER FRACTIONS FICUS DICRANOSTYLA MILDBREAD LEAVES IN VITRO ASSESSMENT ANTIMICROBIAL ACTIVITIES EXTRACTS YEMENI FAGONIA SCHWEINFURTHII HADIDI CYTOTOXIC EFFECT, POTENTIAL, PHYTOCHEMICAL STUDY THE ETHYL ACETATE EXTRACT PLEIOGYNIUM TIMORENSE SEEDS